Pan Fried Garlic Lime Tilapia

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Pan-Fried Garlic Lime Tilapia is a fast, flavorful recipe made with just a few pantry ingredients. The mild fish soaks up the garlic, lime, and buttery seasoning mix, giving you a simple weeknight meal that tastes fresh, bright, and far from boring.

194 CAL 1g CARBS 7g FAT 32g PROTEIN 3
7 Comments

Tilapia sometimes gets a bad reputation for being bland, but that's exactly why I love using it in quick skillet recipes like this Pan-Fried Garlic Lime Tilapia. Its mild flavor is the perfect canvas for bold ingredients, and a mix of butter, garlic, Old Bay, and fresh lime juice transforms it into a bright, delicious meal in just 20 minutes.

This is one of those dinners I make when I want something light but flavorful, especially on nights when I don't want to turn on the oven or babysit a long recipe. The fish cooks fast, develops a nice golden crust in the pan, and the lime juice brings everything to life at the very end. Even picky eaters or "I don't love fish" people tend to enjoy tilapia because it's mild and not "fishy" at all!

Pan fried tilapia with garlic, fresh lime juice, butter, and Old Bay seasoning on a plate with lime slices and green onions.

Before You Get Started

A few helpful things to know before you start:

  • Pat the fish dry first. This helps the seasoning stick and gives the fish a better sear. If your filets are frozen, make sure they're fully thawed and patted dry.
  • Choose the right pan. A heavy skillet (cast iron or stainless steel) gives the best golden crust. Nonstick works too! Just heat it well before adding the fish.
  • Fresh lime makes a difference. Bottled lime juice works in a pinch, but fresh lime gives the sauce a cleaner, brighter flavor.
  • Use ghee if needed. It gives you a buttery flavor with almost no lactose and holds up well to high heat. If you don't have any, use any neutral-flavored oil with a high smoke point.

How to Make Pan-Fried Garlic Lime Tilapia

Once your ingredients are prepped, this recipe comes together fast.

1. Season the Fish

Pat the tilapia dry and coat both sides generously with Old Bay or your favorite seafood seasoning.

2. Sauté the Garlic

Melt the butter (or ghee) in a large skillet over medium heat. Add garlic and cook just until fragrant.

3. Cook the Tilapia

Lay the filets in the skillet and cook until golden and flaky.

4. Finish with Lime

Pour the lime juice over the fish and cook, spooning the sauce over the filets.

Recipe Tips and Tricks

Here's how to make this recipe even easier and more flavorful:

  • Don't flip too early. Tilapia releases easily once it forms a crust. If it's sticking, give it another minute.
  • Use thin tilapia filets for best results. They cook evenly and stay tender.
  • Make it spicy. Add crushed red pepper or cayenne to the seasoning.
  • Add freshness. Sprinkle chopped cilantro or parsley on top before serving.
  • Swap the seasoning. Cajun Seasoning, Lemon Pepper Seasoning, or chili-lime seasoning also work great.

Garlic tilapia that has been pan fried with butter and Old Bay seasoning on a plate with a fork and knife.

Serving Suggestions

Here are some delicious ideas for serving this tilapia so that it feels new and interesting:

  • Make fish tacos: Tilapia is a perfect protein for adding to your fish tacos, and this recipe for fish tacos and avocado crema has the ideal flavor.
  • Make a salad: Add this fish to the top of a light summer salad with your favorite veggies. Top it off with a drizzle of cilantro-lime yogurt dressing.
  • Add grains: This tilapia would work really well on top of some brown rice or quinoa. Add your favorite toppings and sauce!
  • Make it tropical: Serve this pan-fried fish with a side of black beans, sushi rice, and mango salsa for a tropical-style meal!

Storage and Reheating

If you have leftovers, here's how to keep them fresh and reheat them without drying out the fish.

  • Store: Keep leftovers in an airtight container for up to 2 days.
  • Reheat: Warm gently in a skillet or microwave—tilapia reheats quickly, so heat just until warm to avoid drying it out.
  • Freeze: Best enjoyed fresh, but cooked tilapia can be frozen up to 2 months if needed.

Frequently Asked Questions

Here are some of the most commonly asked questions about this recipe:

Yes, you can, but know going into it that it will change the flavor of your fish and may seem even brighter and more citrusy.

 

Yes and no. The acid from the lime juice does change the structure of the proteins in the fish meat so that it essentially "cooks" the fish without adding heat. But, you still need to follow the instructions listed in the recipe card below and cook the fish in the pan.>/p>

 

As a very thin fish, it doesn't take long to cook tilapia. Make sure to get a good sear on both sides, and by that time, your fish will probably be perfectly cooked. A good way to check for doneness is to poke a fork into the thickest part of your filet. If it's white and easily flakes, it's done.

 

Yes, you could bake this lime fish recipe instead of pan-searing it! I would recommend doing it in a 375-degree oven for about 8-12 minutes. However, if you like a crispy crust on your fish, stick with this pan-searing method.

 

The Recipe
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Pan Fried Garlic Lime Tilapia

194 CAL 1g CARBS 7g FAT 32g PROTEIN 3
PREP TIME: 5 Min
COOK TIME: 15 Min
TOTAL TIME: 20 Min
7 Comments
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Ingredients

US METRICS
  • 30 oz. tilapia filets
  • 2.5 tbsp. butter (or ghee)
  • 2 garlic cloves, minced (or more)
  • 1 tbsp. Old Bay (or seafood seasoning)
  • 2.5 tbsp. lime juice

Instructions

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1

Season the fish liberally with Old Bay or seafood seasoning.

Seafood seasoning being sprinkled on two pieces of tilapia.
2

Melt the butter in a skillet and add the garlic. Once fragrant, add the fish and cook for 3-4 minutes per side.

Tilapia frying in a pan with seafood seasoning, garlic, and butter.
3

Add the lime juice over top and cook for 2 more minutes until fish is nice and flaky.

Lime juice being squeezed on tilapia in a pan.

Equipment

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Nutritional Facts
Serving Size: 6 oz.
Amount Per Serving
Calories 194
Calories from Fat 78
% Daily Value *
Total Fat 7g
13%
Saturated Fat 5g
23%
Monounsaturated Fat 0g
0%
Polyunsaturated Fat 0g
0%
Cholesterol 100mg
33%
Sodium 716mg
31%
Total Carbohydrate 1g
0%
Dietary Fiber 0g
0%
Sugars 0g
Protein 32g

* Percent Daily Values are based on a 2,000 calorie diet. Your daily values may be higher or lower depending on your calorie needs.

The Nutritional Values provided are estimates only and may vary based on the preparation method.

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About the author Meet Kristen McCaffrey
Hi, I’m the cookbook author, recipe developer, and food enthusiast behind Slender Kitchen. I am obsessed with making healthy food that is easy to prepare and absolutely delicious. Meal planning is my secret weapon and I hope I can make meal time easier for you with our tried and tested recipes and foolproof meal plans. Learn More
7 Comments
On Pan Fried Garlic Lime Tilapia
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Sue
December 7, 2025 - 18:31
What is the green pieces sprinkled over the top?
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December 8, 2025 - 12:49
Sliced chives! You could add chives, cilantro, or parsley for a little extra flavor.
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Ertha Patrick
May 4, 2024 - 15:14
Add a Rating:
5
Thanks so much! So easy and delicious!
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Janine
June 15, 2023 - 22:54
Add a Rating:
5
Made this for dinner tonight with lime & cilantro rice & sauteed squash. Definitely a hit & making it again. Even my picky granddaughter ate it
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eileen
March 7, 2023 - 16:05
Add a Rating:
5
loved it! so tasty and easy to make!
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Ana Bowman
September 13, 2021 - 18:43
It was easy and very good
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Kathryn
August 1, 2018 - 13:18
Add a Rating:
5
So quick and easy ty
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