Preheat the oven to 450 degrees. In a small bowl, combine the paprika, onion powder, garlic powder, salt, thyme, black pepper, and chili powder. For a spicier chicken breast, add more chili powder or a pinch of cayenne pepper.
Place the entire skillet in the oven and cook for 10-14 minutes until the chicken is fully cooked. The exact cooking time will depend on the thickness of the chicken. Let the chicken rest for 5 minutes. Slice and serve.